Ingredient Directory
Low ConcernVegan

Arginine

L-Arginine / 2-Amino-5-guanidinopentanoic acid

Safety Notes

Amino acid; supports collagen synthesis and nitric oxide production; humectant properties; in hair care, fills cortex damage; at higher concentrations alkaline, can increase hair cuticle swelling (useful in bleach recovery products); generally low sensitization risk

Function & Common Use

Function

Skin Conditioning / Antioxidant / Hair Conditioning

Category

Conditioner

Common In

Hair care skin care anti-aging serums

Origin

Synthetic / Fermentation

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked

Korea (MFDS)

No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Arginine safe to use in skincare?

Arginine has a Low concern rating from The Clean Sheet. Amino acid; supports collagen synthesis and nitric oxide production; humectant properties; in hair care, fills cortex damage; at higher concentrations alkaline, can increase hair cuticle swelling (useful in bleach recovery products); generally low sensitization risk

Is Arginine allowed in India?

Arginine is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Arginine used for in cosmetics?

Arginine functions as: Skin Conditioning / Antioxidant / Hair Conditioning. It is commonly found in: Hair care skin care anti-aging serums.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Canada (NHPID)
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

Identifiers

CAS74-79-3
EC200-811-1

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