Low ConcernVegan

Dimethyl Isosorbide (Sugar-Based Ester Variant)

Isosorb-based penetration enhancer (COSMOS-approved)

Safety Notes

COSMOS-approved penetration enhancer derived from sorbitol (sugar); see Dimethyl Isosorbide main entry for full detail; this entry notes COSMOS-approved sourcing chain

Function & Common Use

Function

Solvent / Penetration Enhancer

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked

Korea (MFDS)

No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Dimethyl Isosorbide (Sugar-Based Ester Variant) safe to use in skincare?

Dimethyl Isosorbide (Sugar-Based Ester Variant) has a Low concern rating from The Clean Sheet. COSMOS-approved penetration enhancer derived from sorbitol (sugar); see Dimethyl Isosorbide main entry for full detail; this entry notes COSMOS-approved sourcing chain

Is Dimethyl Isosorbide (Sugar-Based Ester Variant) allowed in India?

Dimethyl Isosorbide (Sugar-Based Ester Variant) is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Dimethyl Isosorbide (Sugar-Based Ester Variant) used for in cosmetics?

Dimethyl Isosorbide (Sugar-Based Ester Variant) functions as: Solvent / Penetration Enhancer. It is commonly found in: Active delivery vehicles COSMOS products.

TCS Assessment

Low Concern

Data Confidence

High

Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.