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Ethyl Lauroyl Arginate HCl

Ethyl-N-alpha-lauroyl-L-arginate hydrochloride (LAE)

Safety Notes

Cationic broad-spectrum preservative effective against bacteria, yeast and mould at low levels. EU Annex V restricts concentration to 0.4% and excludes lip, oral and mucous-membrane-exposure and spray applications. Can be irritating to eyes/mucosa at higher levels.

Function & Common Use

Function

Preservative (broad-spectrum antimicrobial)

Category

Preservative / Antimicrobial

Common In

Deodorants, some rinse-off and leave-on skincare, wet wipes

Origin

Derived from lauric acid, L-arginine and ethanol

Concentration Limits

India (CDSCO)

No specific limit under CR 2020 in source checked

EU Cosmetics Reg.

0.4% as a preservative; not permitted in lip products, oral-care products or products that may lead to exposure of the end user's mucous membranes, or in sprayable applications (per Annex V restrictions)

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked

Korea (MFDS)

Per MFDS preservative limit (about 0.4%)

Baby restriction: Use with caution; assess mucous-membrane exposure per Annex V restrictions

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Ethyl Lauroyl Arginate HCl safe to use in skincare?

Ethyl Lauroyl Arginate HCl has a Medium concern rating. Cationic broad-spectrum preservative effective against bacteria, yeast and mould at low levels. EU Annex V restricts concentration to 0.4% and excludes lip, oral and mucous-membrane-exposure and spray applications. Can be irritating to eyes/mucosa at higher levels.

Is Ethyl Lauroyl Arginate HCl allowed in India?

Ethyl Lauroyl Arginate HCl is currently classified as "Regulated as a cosmetic ingredient/preservative under CR 2020; verify permitted-preservative listing" under Indian cosmetics regulations. The maximum permitted concentration is No specific limit under CR 2020 in source checked.

What is Ethyl Lauroyl Arginate HCl used for in cosmetics?

Ethyl Lauroyl Arginate HCl functions as: Preservative (broad-spectrum antimicrobial). It is commonly found in: Deodorants, some rinse-off and leave-on skincare, wet wipes.

Is Ethyl Lauroyl Arginate HCl safe for babies?

Ethyl Lauroyl Arginate HCl has baby/child restrictions: Use with caution; assess mucous-membrane exposure per Annex V restrictions. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.

TCS Assessment
Medium Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Regulated as a cosmetic ingredient/preservative under CR 2020; verify permitted-preservative listing
EU
Permitted preservative - Annex V (restricted)
US FDA
Permitted; no specific 21 CFR cosmetic restriction identified in source checked
Korea (MFDS)
Permitted preservative subject to concentration limit per MFDS
Australia (TGA)
Cosmetic ingredient under AICIS; standard framework applies; no therapeutic listing unless therapeutic claims made
Canada (NHPID)
Not listed as restricted on Health Canada Cosmetic Ingredient Hotlist in source checked; standard cosmetic notification applies

EU Annex: Annex V entry 58

Identifiers

CAS60372-77-2
EC434-630-6

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