Ingredient Directory
High ConcernVegan Evaluator Flag

Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde

4-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde; HICC; Lyral

Safety Flags
Allergen: Yes - EU Annex III fragrance allergen (formerly; now moved to Annex II - banned)
Safety Notes

BANNED in EU cosmetics since August 23, 2019 (placed on market) and August 23, 2021 (sale deadline) under Commission Regulation (EU) 2017/1410 placing it in Annex II; one of the most potent contact allergens ever used in cosmetics - sensitization rates as high as 2-3% of patch-tested population; IFRA also banned; India has no explicit ban but SCCS/IFRA guidance applies; TCS highest concern - must be flagged in any product

Function & Common Use

Function

Fragrance / Perfuming / Aroma Chemical

Category

Fragrance Materials

Common In

Formerly used in lily-of-the-valley, muguet, floral, and fresh perfumes; now globally phased out by responsible manufacturers

Origin

Synthetic

Concentration Limits

India (CDSCO)

No specific ban; follow IFRA guidance; use with caution

EU Cosmetics Reg.

BANNED - 0% permitted in all cosmetic products in EU since August 23, 2021 (enforcement date)

US FDA (21 CFR)

No federal ban; IFRA-based voluntary restrictions

Korea (MFDS)

Restricted; declaration required

Format restriction: EU: completely banned in all cosmetic products (Annex II) since Commission Regulation (EU) 2017/1410; IFRA: banned under IFRA standards

Baby restriction: Yes

Pregnancy: No

IFRA: Banned by IFRA - prohibited in all product categories

Frequently Asked Questions

Is Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde safe to use in skincare?

Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde has a High concern rating. BANNED in EU cosmetics since August 23, 2019 (placed on market) and August 23, 2021 (sale deadline) under Commission Regulation (EU) 2017/1410 placing it in Annex II; one of the most potent contact allergens ever used in cosmetics - sensitization rates as high as 2-3% of patch-tested population; IFRA also banned; India has no explicit ban but SCCS/IFRA guidance applies; TCS highest concern - must be flagged in any product

Is Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde allowed in India?

Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde is currently classified as "Restricted" under Indian cosmetics regulations. The maximum permitted concentration is No specific ban; follow IFRA guidance; use with caution.

What is Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde used for in cosmetics?

Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde functions as: Fragrance / Perfuming / Aroma Chemical. It is commonly found in: Formerly used in lily-of-the-valley, muguet, floral, and fresh perfumes; now globally phased out by responsible manufacturers.

Can Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde cause an allergic reaction?

Yes. Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde has an allergen flag (Yes - EU Annex III fragrance allergen (formerly; now moved to Annex II - banned)). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.

Is Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde safe for babies?

Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde has baby/child restrictions: Yes. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.

TCS Assessment
High Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Restricted
EU
Banned
US FDA
Permitted
Korea (MFDS)
Restricted
Australia (TGA)
Permitted
Canada (NHPID)
Permitted

EU Annex: Annex II (banned substance - prohibited in cosmetic products)

Identifiers

CAS31906-04-4
EC250-863-4

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