Ingredient Directory
Low Concern

Madecassoside

Triterpenoid saponin from Centella asiatica

Safety Flags
Allergen: Botanical sensitivity possible; not an EU fragrance allergen in source checked
Safety Notes

Isolated Centella marker compound; do not treat as equivalent to whole Centella extract. Verify purity and assay.

Function & Common Use

Function

Antioxidant / Skin conditioning

Category

Botanical Active

Common In

Cica creams, calming serums, barrier moisturisers

Origin

Plant derived

Concentration Limits

India (CDSCO)

No limit verified

EU Cosmetics Reg.

No maximum identified in source checked

US FDA (21 CFR)

No limit verified

Korea (MFDS)

No limit verified

Format restriction: No specific format restriction identified

Baby restriction: Requires finished product pediatric safety review

Pregnancy: No specific restriction identified; assess full formula and claims

Frequently Asked Questions

Is Madecassoside safe to use in skincare?

Madecassoside has a Low concern rating from The Clean Sheet. Isolated Centella marker compound; do not treat as equivalent to whole Centella extract. Verify purity and assay.

Is Madecassoside allowed in India?

Madecassoside is currently classified as "Not specifically restricted in source checked; verify under India CR 2020 at product review" under Indian cosmetics regulations. The maximum permitted concentration is No limit verified.

What is Madecassoside used for in cosmetics?

Madecassoside functions as: Antioxidant / Skin conditioning. It is commonly found in: Cica creams, calming serums, barrier moisturisers.

Can Madecassoside cause an allergic reaction?

Yes. Madecassoside has an allergen flag (Botanical sensitivity possible; not an EU fragrance allergen in source checked). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.

Is Madecassoside safe for babies?

Madecassoside has baby/child restrictions: Requires finished product pediatric safety review. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.

TCS Assessment
Low Concern
Data Confidence
Medium
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Not specifically restricted in source checked; verify under India CR 2020 at product review
EU
CosIng listed; no EU Annex II to VI restriction identified in source checked
US FDA
No specific cosmetic restriction verified in source checked; claims must remain cosmetic
Korea (MFDS)
Not specifically restricted in source checked; functional claim review required if used for whitening or wrinkle claims
Australia (TGA)
Not a TGA therapeutic sunscreen active; cosmetic use requires claim review
Canada (NHPID)
Not verified in NHPID source checked

EU Annex: Not listed in Annex II to VI in source checked

Identifiers

CAS34540-22-2
EC252-076-1

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