Ingredient Directory
Low ConcernVegan

Pyridoxine HCl

Pyridoxine hydrochloride; 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride

Safety Flags
Safety Notes

Water-soluble Vitamin B6 form; helps regulate sebum production and supports skin barrier function; used in anti-hair loss topical treatments; well tolerated at cosmetic use concentrations.

Function & Common Use

Function

Antioxidant / Skin-Conditioning Agent / Hair Conditioning Agent

Category

Vitamins

Common In

Hair loss treatments, scalp serums, anti-sebum formulas, skin serums

Origin

Synthetic

Concentration Limits

India (CDSCO)

None

EU Cosmetics Reg.

None

US FDA (21 CFR)

None

Korea (MFDS)

None

Format restriction: None

Baby restriction: No

Pregnancy: No

IFRA: No

Frequently Asked Questions

Is Pyridoxine HCl safe to use in skincare?

Pyridoxine HCl has a Low concern rating from The Clean Sheet. Water-soluble Vitamin B6 form; helps regulate sebum production and supports skin barrier function; used in anti-hair loss topical treatments; well tolerated at cosmetic use concentrations.

Is Pyridoxine HCl allowed in India?

Pyridoxine HCl is currently classified as "Permitted" under Indian cosmetics regulations. The maximum permitted concentration is None.

What is Pyridoxine HCl used for in cosmetics?

Pyridoxine HCl functions as: Antioxidant / Skin-Conditioning Agent / Hair Conditioning Agent. It is commonly found in: Hair loss treatments, scalp serums, anti-sebum formulas, skin serums.

Can Pyridoxine HCl cause an allergic reaction?

Yes. Pyridoxine HCl has an allergen flag (No). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.

Is Pyridoxine HCl safe for babies?

Pyridoxine HCl has baby/child restrictions: No. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies
Canada (NHPID)
Not specifically restricted; standard Health Canada cosmetic notification applies

EU Annex: None

Identifiers

CAS58-56-0
EC200-386-2

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