Ingredient Directory
Low ConcernVegan

Superoxide Dismutase

Superoxide dismutase; superoxide:superoxide oxidoreductase (EC 1.15.1.1)

Safety Flags
Safety Notes

Antioxidant enzyme that catalyzes dismutation of superoxide radical; typically derived from bovine liver or recombinant biotechnology; large molecular size limits skin penetration; well tolerated.

Function & Common Use

Function

Antioxidant / Enzyme / Skin-Conditioning Agent

Category

Antioxidants

Common In

Anti-aging creams, post-procedure skincare, antioxidant serums

Origin

Biotechnology / Natural

Concentration Limits

India (CDSCO)

None

EU Cosmetics Reg.

None

US FDA (21 CFR)

None

Korea (MFDS)

None

Format restriction: None

Baby restriction: No

Pregnancy: No

IFRA: No

Frequently Asked Questions

Is Superoxide Dismutase safe to use in skincare?

Superoxide Dismutase has a Low concern rating from The Clean Sheet. Antioxidant enzyme that catalyzes dismutation of superoxide radical; typically derived from bovine liver or recombinant biotechnology; large molecular size limits skin penetration; well tolerated.

Is Superoxide Dismutase allowed in India?

Superoxide Dismutase is currently classified as "Permitted" under Indian cosmetics regulations. The maximum permitted concentration is None.

What is Superoxide Dismutase used for in cosmetics?

Superoxide Dismutase functions as: Antioxidant / Enzyme / Skin-Conditioning Agent. It is commonly found in: Anti-aging creams, post-procedure skincare, antioxidant serums.

Can Superoxide Dismutase cause an allergic reaction?

Yes. Superoxide Dismutase has an allergen flag (No). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.

Is Superoxide Dismutase safe for babies?

Superoxide Dismutase has baby/child restrictions: No. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.

TCS Assessment
Low Concern
Data Confidence
Medium
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies
Canada (NHPID)
Not specifically restricted; standard Health Canada cosmetic notification applies

EU Annex: None

Identifiers

CAS9054-89-1
EC232-943-6

Want to check if your product contains Superoxide Dismutase?

Analyse a Product
WhatsApp Community

Join The Clean Sheet™ community

Science-backed beauty tips, ingredient alerts, and early access. Straight to your WhatsApp.

Join for free →