Tazarotene
Ethyl 6-[(4,4-dimethylthiochroman-6-yl)ethynyl]nicotinate; ethyl (E)-6-[2-(4,4-dimethylthiochroman-6-yl)vinyl]-3-pyridinecarboxylate
Acetylenic retinoid; potent teratogen - strictly contraindicated in pregnancy and women of childbearing potential without contraception; prescription-only everywhere; causes severe photosensitivity and skin irritation.
Function & Common Use
Retinoid / Keratolytic / Anti-acne / Anti-psoriatic (Rx only)
Vitamins
Prescription acne and psoriasis treatments (Tazorac, Avage)
Synthetic
Concentration Limits
Not permitted in cosmetics; Schedule H prescription drug
Not permitted as cosmetic ingredient in EU
Not permitted in cosmetics; Rx drug only (0.045%-0.1% lotion/cream)
Not permitted in cosmetics; Rx prescription only
Format restriction: PRESCRIPTION ONLY in all markets globally; not a cosmetic ingredient in any jurisdiction
Baby restriction: Yes
Pregnancy: Yes
IFRA: No
Frequently Asked Questions
Is Tazarotene safe to use in skincare?
Tazarotene has a High concern rating. Acetylenic retinoid; potent teratogen - strictly contraindicated in pregnancy and women of childbearing potential without contraception; prescription-only everywhere; causes severe photosensitivity and skin irritation.
Is Tazarotene allowed in India?
Tazarotene is currently classified as "Restricted - Prescription Only Drug (Schedule H)" under Indian cosmetics regulations. The maximum permitted concentration is Not permitted in cosmetics; Schedule H prescription drug.
What is Tazarotene used for in cosmetics?
Tazarotene functions as: Retinoid / Keratolytic / Anti-acne / Anti-psoriatic (Rx only). It is commonly found in: Prescription acne and psoriasis treatments (Tazorac, Avage).
Can Tazarotene cause an allergic reaction?
Yes. Tazarotene has an allergen flag (No). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.
Is Tazarotene safe for babies?
Tazarotene has baby/child restrictions: Yes. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.
Regulatory Status
EU Annex: None
Identifiers
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