Ingredient Directory
Low ConcernVegan

Vitis Vinifera (Grape) Seed Extract

Grape seed extract

Safety Flags
Allergen: Botanical sensitivity possible - grape/wine allergy cross-reactivity in rare cases
Safety Notes

Rich in oligomeric proanthocyanidins (OPCs); not an irritant or sensitizer; no systemic toxicity in long-term repeat-dose studies; well tolerated across skin types

Function & Common Use

Function

Antioxidant, skin conditioning, astringent

Category

Botanical Extract

Common In

Anti-ageing serums, antioxidant moisturisers, eye creams, hair care

Origin

Plant derived

Concentration Limits

India (CDSCO)

Not verified in source checked

EU Cosmetics Reg.

No limit specified

US FDA (21 CFR)

No limit; CIR concluded safe as used

Korea (MFDS)

Not verified in source checked

Pregnancy: No specific restriction identified

Frequently Asked Questions

Is Vitis Vinifera (Grape) Seed Extract safe to use in skincare?

Vitis Vinifera (Grape) Seed Extract has a Low concern rating from The Clean Sheet. Rich in oligomeric proanthocyanidins (OPCs); not an irritant or sensitizer; no systemic toxicity in long-term repeat-dose studies; well tolerated across skin types

Is Vitis Vinifera (Grape) Seed Extract allowed in India?

Vitis Vinifera (Grape) Seed Extract is currently classified as "Not specifically restricted in source checked" under Indian cosmetics regulations. The maximum permitted concentration is Not verified in source checked.

What is Vitis Vinifera (Grape) Seed Extract used for in cosmetics?

Vitis Vinifera (Grape) Seed Extract functions as: Antioxidant, skin conditioning, astringent. It is commonly found in: Anti-ageing serums, antioxidant moisturisers, eye creams, hair care.

Can Vitis Vinifera (Grape) Seed Extract cause an allergic reaction?

Yes. Vitis Vinifera (Grape) Seed Extract has an allergen flag (Botanical sensitivity possible - grape/wine allergy cross-reactivity in rare cases). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Not specifically restricted in source checked
EU
Permitted - listed in EU CosIng; not in Annex II or Annex III
US FDA
Permitted for cosmetic use; CIR Safety Assessment 2014 concluded safe as used; no systemic toxicity observed in oral or repeat-dose studies
Korea (MFDS)
Not specifically restricted in source checked - general cosmetic ingredient under MFDS negative list system
Australia (TGA)
Permitted as cosmetic ingredient under AICIS; no specific restriction found
Canada (NHPID)
Not verified in source checked

EU Annex: None

Identifiers

CAS84929-27-1
EC284-511-6

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