Ingredient Directory
Medium ConcernVegan Evaluator Flag

Zinc Pyrithione

Zinc 2-mercaptopyridine-1-oxide / Pyrithione zinc

Safety Notes

Effective antifungal/antibacterial against Malassezia; EU Annex V preservative; US OTC monograph antidandruff drug at 0.3-1% (drug product in US); environmental concern, aquatic toxicity (TCS should flag in Layer 5C); drug/cosmetic boundary critical in India and US claim assessment

Function & Common Use

Function

Active (antidandruff) / Preservative

Category

Preservative

Common In

Antidandruff shampoos scalp treatments body wash (seborrheic dermatitis)

Origin

Synthetic

Concentration Limits

India (CDSCO)

1% max

EU Cosmetics Reg.

EU Annex V: 1% rinse-off hair and body wash; 0.5% other rinse-off; not in aerosol/spray

Format restriction: Rinse-off

Frequently Asked Questions

Is Zinc Pyrithione safe to use in skincare?

Zinc Pyrithione has a Medium concern rating. Effective antifungal/antibacterial against Malassezia; EU Annex V preservative; US OTC monograph antidandruff drug at 0.3-1% (drug product in US); environmental concern, aquatic toxicity (TCS should flag in Layer 5C); drug/cosmetic boundary critical in India and US claim assessment

Is Zinc Pyrithione allowed in India?

Zinc Pyrithione is currently classified as "Permitted as OTC in some markets" under Indian cosmetics regulations. The maximum permitted concentration is 1% max.

What is Zinc Pyrithione used for in cosmetics?

Zinc Pyrithione functions as: Active (antidandruff) / Preservative. It is commonly found in: Antidandruff shampoos scalp treatments body wash (seborrheic dermatitis).

TCS Assessment
Medium Concern
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted as OTC in some markets
EU
Permitted
US FDA
Permitted with limits
Korea (MFDS)
Permitted

EU Annex: Annex V

Identifiers

CAS13463-41-7
EC236-671-3

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