Ingredient Directory
Low ConcernVegan Evaluator Flag

Acetyl Hexapeptide-3

Leuphasyl / Argireline

Safety Notes

'Botox-like' marketing claims must be carefully reviewed, cosmetic claims of 'relaxes expression lines' are permissible; claims of 'acts like Botox' or 'same as injections' are not; typically 5-10% in finished product formula

Function & Common Use

Function

Active (Peptide / Anti-aging)

Category

Active Ingredient

Common In

Anti-aging serums eye creams

Origin

Synthetic

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked

Korea (MFDS)

No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category

Format restriction: Leave-on

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Acetyl Hexapeptide-3 safe to use in skincare?

Acetyl Hexapeptide-3 has a Low concern rating from The Clean Sheet. 'Botox-like' marketing claims must be carefully reviewed, cosmetic claims of 'relaxes expression lines' are permissible; claims of 'acts like Botox' or 'same as injections' are not; typically 5-10% in finished product formula

Is Acetyl Hexapeptide-3 allowed in India?

Acetyl Hexapeptide-3 is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Acetyl Hexapeptide-3 used for in cosmetics?

Acetyl Hexapeptide-3 functions as: Active (Peptide / Anti-aging). It is commonly found in: Anti-aging serums eye creams.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Canada (NHPID)
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

Identifiers

CAS616204-22-9
ECN/A

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