Low ConcernVegan Evaluator Flag

Adenosine

Safety Notes

Anti-wrinkle active; MFDS-approved functional cosmetic active in Korea; 0.04% Korea-approved concentration; good safety profile

Function & Common Use

Function

Active (Anti-aging)

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked

Korea (MFDS)

0.04% (wrinkle improvement functional cosmetic)

Format restriction: Leave-on

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Adenosine safe to use in skincare?

Adenosine has a Low concern rating from The Clean Sheet. Anti-wrinkle active; MFDS-approved functional cosmetic active in Korea; 0.04% Korea-approved concentration; good safety profile

Is Adenosine allowed in India?

Adenosine is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Adenosine used for in cosmetics?

Adenosine functions as: Active (Anti-aging). It is commonly found in: Anti-aging serums moisturisers.

TCS Assessment

Low Concern

Data Confidence

High

Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)

Permitted

US FDA

Permitted

Korea (MFDS)

Korea: functional cosmetic (anti-wrinkle approved)

Australia (TGA)

Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made

Canada (NHPID)

Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

Identifiers

CAS58-61-7

EC200-381-5

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