Ingredient Directory
Low ConcernVegan Evaluator Flag

Acetyl Tetrapeptide-5

Vialox-inspired depuffing peptide

Safety Notes

Tetrapeptide active for reducing eye puffiness; mechanism: reduces water retention and vascular permeability in periorbital area; clinical data largely from brand-commissioned research; well-tolerated; eye-area safe

Function & Common Use

Function

Active (anti-puffiness peptide)

Category

Active Ingredient

Common In

Eye creams depuffing serums

Origin

Synthetic

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

Format restriction: Leave-on

Frequently Asked Questions

Is Acetyl Tetrapeptide-5 safe to use in skincare?

Acetyl Tetrapeptide-5 has a Low concern rating from The Clean Sheet. Tetrapeptide active for reducing eye puffiness; mechanism: reduces water retention and vascular permeability in periorbital area; clinical data largely from brand-commissioned research; well-tolerated; eye-area safe

Is Acetyl Tetrapeptide-5 allowed in India?

Acetyl Tetrapeptide-5 is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Acetyl Tetrapeptide-5 used for in cosmetics?

Acetyl Tetrapeptide-5 functions as: Active (anti-puffiness peptide). It is commonly found in: Eye creams depuffing serums.

TCS Assessment
Low Concern
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted

Identifiers

CAS820959-17-9
ECN/A

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