The Clean Sheet
Ingredient Directory
Low ConcernVegan

Bromelain

Proteolytic enzyme complex from Ananas comosus (pineapple)

Safety Flags
Allergen: Enzyme sensitiser potential; patch test advised; avoid inhalation of powder
Safety Notes

Pineapple-derived protease used for gentle surface exfoliation and radiance. As with other enzymes, sensitisation possible; finished topical formulas generally well tolerated

Function & Common Use

Function

Enzymatic exfoliant, keratolytic active

Category

Active Ingredient

Common In

Enzyme masks, brightening cleansers, exfoliating peels

Origin

Plant derived (pineapple stem/fruit)

Concentration Limits

India (CDSCO)

Not verified in source checked

EU Cosmetics Reg.

No limit specified

US FDA (21 CFR)

No limit established

Korea (MFDS)

Not verified in source checked

Pregnancy: No specific restriction identified for topical cosmetic use

Frequently Asked Questions

Is Bromelain safe to use in skincare?

Bromelain has a Low concern rating from The Clean Sheet. Pineapple-derived protease used for gentle surface exfoliation and radiance. As with other enzymes, sensitisation possible; finished topical formulas generally well tolerated

Is Bromelain allowed in India?

Bromelain is currently classified as "Not specifically restricted in source checked; traditional cosmetic/Ayurvedic botanical with long history of use; no known CDSCO restriction" under Indian cosmetics regulations. The maximum permitted concentration is Not verified in source checked.

What is Bromelain used for in cosmetics?

Bromelain functions as: Enzymatic exfoliant, keratolytic active. It is commonly found in: Enzyme masks, brightening cleansers, exfoliating peels.

Can Bromelain cause an allergic reaction?

Yes. Bromelain has an allergen flag (Enzyme sensitiser potential; patch test advised; avoid inhalation of powder). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Not specifically restricted in source checked; traditional cosmetic/Ayurvedic botanical with long history of use; no known CDSCO restriction
EU
Permitted - listed in EU CosIng; not in Annex II or Annex III
US FDA
Permitted for cosmetic use; no restriction identified
Korea (MFDS)
Not specifically restricted in source checked; general cosmetic ingredient under MFDS negative list system
Australia (TGA)
Permitted as cosmetic ingredient under AICIS; no specific restriction found
Canada (NHPID)
Not verified in source checked

EU Annex: None

Identifiers

CAS9001-00-7
EC232-572-4

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