Ingredient Directory
Low Concern

Carnosine

Beta-alanyl-L-histidine / L-Carnosine

Safety Notes

Dipeptide antioxidant; anti-glycation (inhibits Advanced Glycation End-products); declines with age; protects cellular proteins from oxidative and carbonyl stress; growing clinical evidence; animal-derived (historically), synthetic versions available and vegan; blue light protection research emerging

Function & Common Use

Function

Active (antioxidant / anti-glycation)

Category

Active Ingredient

Common In

Anti-aging serums premium moisturisers

Origin

Synthetic / Animal-derived (muscle)

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked

Korea (MFDS)

No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Carnosine safe to use in skincare?

Carnosine has a Low concern rating from The Clean Sheet. Dipeptide antioxidant; anti-glycation (inhibits Advanced Glycation End-products); declines with age; protects cellular proteins from oxidative and carbonyl stress; growing clinical evidence; animal-derived (historically), synthetic versions available and vegan; blue light protection research emerging

Is Carnosine allowed in India?

Carnosine is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Carnosine used for in cosmetics?

Carnosine functions as: Active (antioxidant / anti-glycation). It is commonly found in: Anti-aging serums premium moisturisers.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Canada (NHPID)
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

Identifiers

CAS305-84-0
EC206-169-5

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