Ingredient Directory
Low ConcernVegan

Diacetyl Boldine

Lumiskin / Boldine diacetate

Safety Notes

Diacetate ester of boldine (aporphine alkaloid); antioxidant and tyrosinase inhibitor; clinical data available from brand research; marketed as 'Lumiskin' by Provital; low sensitization risk; well-tolerated

Function & Common Use

Function

Active (brightening / antioxidant)

Category

Active Ingredient

Common In

Brightening serums premium anti-aging products

Origin

Synthetic (from boldine alkaloid)

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No specific limit

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked; EU limit reference: No specific limit

Korea (MFDS)

No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category

Format restriction: Leave-on

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Diacetyl Boldine safe to use in skincare?

Diacetyl Boldine has a Low concern rating from The Clean Sheet. Diacetate ester of boldine (aporphine alkaloid); antioxidant and tyrosinase inhibitor; clinical data available from brand research; marketed as 'Lumiskin' by Provital; low sensitization risk; well-tolerated

Is Diacetyl Boldine allowed in India?

Diacetyl Boldine is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Diacetyl Boldine used for in cosmetics?

Diacetyl Boldine functions as: Active (brightening / antioxidant). It is commonly found in: Brightening serums premium anti-aging products.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Canada (NHPID)
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

Identifiers

CAS514-01-2
EC208-173-1

Want to check if your product contains Diacetyl Boldine?

Analyse a Product
WhatsApp Community

Join The Clean Sheet™ community

Science-backed beauty tips, ingredient alerts, and early access. Straight to your WhatsApp.

Join for free →