Ingredient Directory
Low ConcernVegan

Hydrolyzed Hyaluronic Acid

Low-molecular-weight hydrolysate of hyaluronic acid (enzymatic or acid hydrolysis; MW typically 10-50 kDa)

Safety Flags
Safety Notes

Smaller molecular weight than native HA (10-50 kDa) allowing deeper skin penetration vs high-MW sodium hyaluronate; fragments can stimulate hyaluronic acid synthesis; EU CosIng COSING REF 59169; excellent tolerance profile

Function & Common Use

Function

Humectant / Skin-Conditioning Agent

Category

Humectants

Common In

Anti-aging serums, moisturizers, eye creams, sheet masks

Origin

Biotechnology (enzymatic hydrolysis of fermentation-derived hyaluronic acid)

Concentration Limits

India (CDSCO)

None

EU Cosmetics Reg.

None

US FDA (21 CFR)

None

Korea (MFDS)

None

Format restriction: None

Baby restriction: No

Pregnancy: No

IFRA: No

Frequently Asked Questions

Is Hydrolyzed Hyaluronic Acid safe to use in skincare?

Hydrolyzed Hyaluronic Acid has a Low concern rating from The Clean Sheet. Smaller molecular weight than native HA (10-50 kDa) allowing deeper skin penetration vs high-MW sodium hyaluronate; fragments can stimulate hyaluronic acid synthesis; EU CosIng COSING REF 59169; excellent tolerance profile

Is Hydrolyzed Hyaluronic Acid allowed in India?

Hydrolyzed Hyaluronic Acid is currently classified as "Permitted" under Indian cosmetics regulations. The maximum permitted concentration is None.

What is Hydrolyzed Hyaluronic Acid used for in cosmetics?

Hydrolyzed Hyaluronic Acid functions as: Humectant / Skin-Conditioning Agent. It is commonly found in: Anti-aging serums, moisturizers, eye creams, sheet masks.

Can Hydrolyzed Hyaluronic Acid cause an allergic reaction?

Yes. Hydrolyzed Hyaluronic Acid has an allergen flag (No). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.

Is Hydrolyzed Hyaluronic Acid safe for babies?

Hydrolyzed Hyaluronic Acid has baby/child restrictions: No. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Permitted
Canada (NHPID)
Permitted

EU Annex: None

Identifiers

CAS9004-61-9

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