Ingredient Directory
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Hydroxypinacolone Retinoate

Granactive Retinoid / Retinoate ester

Safety Notes

Retinoic acid ester that binds directly to nuclear retinoic acid receptors without conversion chain; claimed to be non-irritating retinoid; no direct EU restriction yet (regulatory position evolving, check current status); marketed as 'Granactive Retinoid' by Grant Industries; higher cost than retinol; pregnancy: caution (retinoate ester of retinoic acid, precautionary avoidance recommended)

Function & Common Use

Function

Active (retinoid ester)

Category

Active Ingredient

Common In

Serums anti-aging products

Origin

Synthetic

Concentration Limits

India (CDSCO)

No formal limit

EU Cosmetics Reg.

No EU Annex III entry (not explicitly listed, under review)

Format restriction: Leave-on

Baby restriction: Caution in pregnancy, retinoate

Frequently Asked Questions

Is Hydroxypinacolone Retinoate safe to use in skincare?

Hydroxypinacolone Retinoate has a High concern rating. Retinoic acid ester that binds directly to nuclear retinoic acid receptors without conversion chain; claimed to be non-irritating retinoid; no direct EU restriction yet (regulatory position evolving, check current status); marketed as 'Granactive Retinoid' by Grant Industries; higher cost than retinol; pregnancy: caution (retinoate ester of retinoic acid, precautionary avoidance recommended)

Is Hydroxypinacolone Retinoate allowed in India?

Hydroxypinacolone Retinoate is currently classified as "Permitted" under Indian cosmetics regulations. The maximum permitted concentration is No formal limit.

What is Hydroxypinacolone Retinoate used for in cosmetics?

Hydroxypinacolone Retinoate functions as: Active (retinoid ester). It is commonly found in: Serums anti-aging products.

Is Hydroxypinacolone Retinoate safe for babies?

Hydroxypinacolone Retinoate has baby/child restrictions: Caution in pregnancy, retinoate. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.

TCS Assessment
Low-Medium
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted

Identifiers

CAS893412-73-2
ECN/A

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