Ingredient Directory
Low ConcernVegan

Leuphasyl (Dipeptide-2)

Dipeptide-2 / Leuphasyl

Safety Notes

Enkephalin analogue; reduces fluid accumulation in periorbital area; anti-puffiness; clinical evidence for eye bag reduction; well-tolerated; often combined with acetyl tetrapeptide-5

Function & Common Use

Function

Active (anti-wrinkle / anti-puffiness peptide)

Category

Active Ingredient

Common In

Eye creams anti-puffiness serums

Origin

Synthetic

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

Frequently Asked Questions

Is Leuphasyl (Dipeptide-2) safe to use in skincare?

Leuphasyl (Dipeptide-2) has a Low concern rating from The Clean Sheet. Enkephalin analogue; reduces fluid accumulation in periorbital area; anti-puffiness; clinical evidence for eye bag reduction; well-tolerated; often combined with acetyl tetrapeptide-5

Is Leuphasyl (Dipeptide-2) allowed in India?

Leuphasyl (Dipeptide-2) is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Leuphasyl (Dipeptide-2) used for in cosmetics?

Leuphasyl (Dipeptide-2) functions as: Active (anti-wrinkle / anti-puffiness peptide). It is commonly found in: Eye creams anti-puffiness serums.

TCS Assessment
Low Concern
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted

Identifiers

CAS162698-40-0
ECN/A

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