The Clean Sheet
Ingredient Directory
Low ConcernVegan

Madecassic Acid

Pentacyclic triterpene from Centella asiatica

Safety Flags
Allergen: Low
Safety Notes

One of the four principal Centella actives (with asiaticoside, madecassoside, asiatic acid); supports wound-healing and barrier repair pathways. Well tolerated topically

Function & Common Use

Function

Soothing, barrier-repair, skin conditioning active

Category

Active Ingredient

Common In

Cica soothing serums, barrier-repair creams, redness treatments

Origin

Plant derived (Centella asiatica)

Concentration Limits

India (CDSCO)

Not verified in source checked

EU Cosmetics Reg.

No limit specified

US FDA (21 CFR)

No limit established

Korea (MFDS)

Not verified in source checked

Pregnancy: No specific restriction identified for topical cosmetic use

Frequently Asked Questions

Is Madecassic Acid safe to use in skincare?

Madecassic Acid has a Low concern rating from The Clean Sheet. One of the four principal Centella actives (with asiaticoside, madecassoside, asiatic acid); supports wound-healing and barrier repair pathways. Well tolerated topically

Is Madecassic Acid allowed in India?

Madecassic Acid is currently classified as "Not specifically restricted in source checked; traditional cosmetic/Ayurvedic botanical with long history of use; no known CDSCO restriction" under Indian cosmetics regulations. The maximum permitted concentration is Not verified in source checked.

What is Madecassic Acid used for in cosmetics?

Madecassic Acid functions as: Soothing, barrier-repair, skin conditioning active. It is commonly found in: Cica soothing serums, barrier-repair creams, redness treatments.

Can Madecassic Acid cause an allergic reaction?

Yes. Madecassic Acid has an allergen flag (Low). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.

TCS Assessment
Low Concern
Data Confidence
Medium
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Not specifically restricted in source checked; traditional cosmetic/Ayurvedic botanical with long history of use; no known CDSCO restriction
EU
Permitted - listed in EU CosIng; not in Annex II or Annex III
US FDA
Permitted for cosmetic use; no restriction identified
Korea (MFDS)
Not specifically restricted in source checked; general cosmetic ingredient under MFDS negative list system
Australia (TGA)
Permitted as cosmetic ingredient under AICIS; no specific restriction found
Canada (NHPID)
Not verified in source checked

EU Annex: None

Identifiers

CAS18449-41-7

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