Ingredient Directory
Low ConcernVegan

Milk Thistle Extract (Silybum Marianum Fruit Extract)

Silymarin / Milk thistle fruit extract

Safety Notes

Rich in silymarin (silybin and related flavonolignans); potent antioxidant and anti-inflammatory; hepatoprotective (oral); topical antioxidant and soothing; low sensitization risk; Compositae family, but different from Chamomile/Calendula; well-tolerated

Function & Common Use

Function

Active (antioxidant / hepatoprotective)

Category

Active Ingredient

Common In

Antioxidant serums sensitive skin products

Origin

Vegetable (milk thistle fruit)

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked

Korea (MFDS)

No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Milk Thistle Extract (Silybum Marianum Fruit Extract) safe to use in skincare?

Milk Thistle Extract (Silybum Marianum Fruit Extract) has a Low concern rating from The Clean Sheet. Rich in silymarin (silybin and related flavonolignans); potent antioxidant and anti-inflammatory; hepatoprotective (oral); topical antioxidant and soothing; low sensitization risk; Compositae family, but different from Chamomile/Calendula; well-tolerated

Is Milk Thistle Extract (Silybum Marianum Fruit Extract) allowed in India?

Milk Thistle Extract (Silybum Marianum Fruit Extract) is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Milk Thistle Extract (Silybum Marianum Fruit Extract) used for in cosmetics?

Milk Thistle Extract (Silybum Marianum Fruit Extract) functions as: Active (antioxidant / hepatoprotective). It is commonly found in: Antioxidant serums sensitive skin products.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Canada (NHPID)
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

Identifiers

CAS84604-20-6
EC283-298-0

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