Ingredient Directory
Low ConcernVegan

Palmitoyl Proline

Palmitoyl-L-proline

Safety Notes

Fatty acid-proline conjugate; skin conditioning; penetration into lipid bilayer structure; well-tolerated

Function & Common Use

Function

Active (skin conditioning peptide-lipid conjugate)

Category

Active Ingredient

Common In

Specialty serums anti-aging products

Origin

Synthetic

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked

Korea (MFDS)

No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Palmitoyl Proline safe to use in skincare?

Palmitoyl Proline has a Low concern rating from The Clean Sheet. Fatty acid-proline conjugate; skin conditioning; penetration into lipid bilayer structure; well-tolerated

Is Palmitoyl Proline allowed in India?

Palmitoyl Proline is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Palmitoyl Proline used for in cosmetics?

Palmitoyl Proline functions as: Active (skin conditioning peptide-lipid conjugate). It is commonly found in: Specialty serums anti-aging products.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Canada (NHPID)
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

Identifiers

CASN/A
ECN/A

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