Ingredient Directory
Low ConcernVegan

Probiotic Lysate (Lactobacillus Ferment Lysate)

Probiotic postbiotic lysate from Lactobacillus

Safety Notes

Cell wall fragments and metabolites from lysed Lactobacillus; postbiotic (non-living); immune modulation; skin barrier support; anti-inflammatory; emerging evidence; well-tolerated; distinct from Lactobacillus Ferment (alive metabolites)

Function & Common Use

Function

Skin Conditioning / Microbiome Support / Active

Category

Active Ingredient

Common In

Microbiome skincare probiotic skin care serums

Origin

Biotechnological (bacterial fermentation + lysis)

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked

Korea (MFDS)

No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Probiotic Lysate (Lactobacillus Ferment Lysate) safe to use in skincare?

Probiotic Lysate (Lactobacillus Ferment Lysate) has a Low concern rating from The Clean Sheet. Cell wall fragments and metabolites from lysed Lactobacillus; postbiotic (non-living); immune modulation; skin barrier support; anti-inflammatory; emerging evidence; well-tolerated; distinct from Lactobacillus Ferment (alive metabolites)

Is Probiotic Lysate (Lactobacillus Ferment Lysate) allowed in India?

Probiotic Lysate (Lactobacillus Ferment Lysate) is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Probiotic Lysate (Lactobacillus Ferment Lysate) used for in cosmetics?

Probiotic Lysate (Lactobacillus Ferment Lysate) functions as: Skin Conditioning / Microbiome Support / Active. It is commonly found in: Microbiome skincare probiotic skin care serums.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Canada (NHPID)
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

Identifiers

CASN/A
ECN/A

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