Ingredient Directory
Low ConcernVegan

Salicin

D-(-)-Salicin / Willow bark salivary glycoside

Safety Notes

Precursor to salicylates (requires conversion to salicyl alcohol then salicylic acid); anti-inflammatory; mild exfoliant via salicylate pathway; not equivalent to free salicylic acid in concentration terms, claims of salicylic acid equivalence require substantiation; aspirin allergy cross-reactivity possible but lower than free acid

Function & Common Use

Function

Active (anti-inflammatory / mild exfoliant)

Category

Active Ingredient

Common In

Natural exfoliants willow bark extract products

Origin

Vegetable (willow bark)

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

Frequently Asked Questions

Is Salicin safe to use in skincare?

Salicin has a Low concern rating from The Clean Sheet. Precursor to salicylates (requires conversion to salicyl alcohol then salicylic acid); anti-inflammatory; mild exfoliant via salicylate pathway; not equivalent to free salicylic acid in concentration terms, claims of salicylic acid equivalence require substantiation; aspirin allergy cross-reactivity possible but lower than free acid

Is Salicin allowed in India?

Salicin is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Salicin used for in cosmetics?

Salicin functions as: Active (anti-inflammatory / mild exfoliant). It is commonly found in: Natural exfoliants willow bark extract products.

TCS Assessment
Low Concern
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted

Identifiers

CAS138-52-3
EC205-322-4

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