Ingredient Directory
Low ConcernVegan Evaluator Flag

Snap-8 (Acetyl Octapeptide-3)

Octapeptide-3 / SNAP-8

Safety Notes

Extended Argireline (hexapeptide-3); competitive inhibitor of SNARE complex; reduces muscle contraction causing expression lines; clinical evidence at 4%; well-tolerated

Function & Common Use

Function

Active (anti-wrinkle peptide)

Category

Active Ingredient

Common In

Anti-aging serums expression line reduction

Origin

Synthetic

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked

Korea (MFDS)

No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Snap-8 (Acetyl Octapeptide-3) safe to use in skincare?

Snap-8 (Acetyl Octapeptide-3) has a Low concern rating from The Clean Sheet. Extended Argireline (hexapeptide-3); competitive inhibitor of SNARE complex; reduces muscle contraction causing expression lines; clinical evidence at 4%; well-tolerated

Is Snap-8 (Acetyl Octapeptide-3) allowed in India?

Snap-8 (Acetyl Octapeptide-3) is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Snap-8 (Acetyl Octapeptide-3) used for in cosmetics?

Snap-8 (Acetyl Octapeptide-3) functions as: Active (anti-wrinkle peptide). It is commonly found in: Anti-aging serums expression line reduction.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Canada (NHPID)
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

Identifiers

CAS868844-74-0
ECN/A

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