Ingredient Directory
Low ConcernVegan

Ubiquinone

Coenzyme Q10 / Ubiquinone-10

Safety Notes

Endogenous mitochondrial antioxidant; declines with age; topical penetration is limited by large molecular size, surface and upper epidermis effects; clinical evidence for wrinkle reduction accumulating; low sensitization risk; yellow colour can affect formulation aesthetics; reduce: Ubiquinol form better penetration

Function & Common Use

Function

Active (antioxidant / cellular energy)

Category

Active Ingredient

Common In

Anti-aging serums eye creams moisturisers

Origin

Biotechnological / Synthetic

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked

Korea (MFDS)

No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Ubiquinone safe to use in skincare?

Ubiquinone has a Low concern rating from The Clean Sheet. Endogenous mitochondrial antioxidant; declines with age; topical penetration is limited by large molecular size, surface and upper epidermis effects; clinical evidence for wrinkle reduction accumulating; low sensitization risk; yellow colour can affect formulation aesthetics; reduce: Ubiquinol form better penetration

Is Ubiquinone allowed in India?

Ubiquinone is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Ubiquinone used for in cosmetics?

Ubiquinone functions as: Active (antioxidant / cellular energy). It is commonly found in: Anti-aging serums eye creams moisturisers.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Canada (NHPID)
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

Identifiers

CAS303-98-0
EC206-132-3

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