Ingredient Directory
Medium ConcernVegan Evaluator Flag

Benzethonium Chloride

Benzyldimethyl[2-[2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethyl]ammonium chloride

Safety Flags
Allergen: Yes
Safety Notes

Quaternary ammonium compound; can cause sensitization and eye irritation; US FDA removed from OTC antiseptic washes due to lack of safety/efficacy data; allergen potential noted.

Function & Common Use

Function

Preservative, Antimicrobial, Surfactant

Category

Preservatives

Common In

Antiseptic wipes, toners, eye makeup, contact lens solutions

Origin

Synthetic

Concentration Limits

India (CDSCO)

0.1%

EU Cosmetics Reg.

0.1% (rinse-off); 0.05% (leave-on)

US FDA (21 CFR)

0.1% (OTC antimicrobial; FDA banned in OTC antiseptic washes 2017)

Korea (MFDS)

0.1%

Format restriction: EU: not for use in oral hygiene products; US FDA banned from OTC consumer antiseptic wash products (2017 final rule)

Baby restriction: No

Pregnancy: No

IFRA: No

Frequently Asked Questions

Is Benzethonium Chloride safe to use in skincare?

Benzethonium Chloride has a Medium concern rating. Quaternary ammonium compound; can cause sensitization and eye irritation; US FDA removed from OTC antiseptic washes due to lack of safety/efficacy data; allergen potential noted.

Is Benzethonium Chloride allowed in India?

Benzethonium Chloride is currently classified as "Permitted" under Indian cosmetics regulations. The maximum permitted concentration is 0.1%.

What is Benzethonium Chloride used for in cosmetics?

Benzethonium Chloride functions as: Preservative, Antimicrobial, Surfactant. It is commonly found in: Antiseptic wipes, toners, eye makeup, contact lens solutions.

Can Benzethonium Chloride cause an allergic reaction?

Yes. Benzethonium Chloride has an allergen flag (Yes). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.

Is Benzethonium Chloride safe for babies?

Benzethonium Chloride has baby/child restrictions: No. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.

TCS Assessment
Medium Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Restricted
Korea (MFDS)
Permitted
Australia (TGA)
Permitted
Canada (NHPID)
Permitted

EU Annex: Annex V (permitted preservative)

Identifiers

CAS121-54-0
EC204-479-9

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