Ingredient Directory
Low ConcernVegan

Climbazole

1-[4-Chloro-2-(2-chlorophenyl)-1,3-dioxolan-2-ylmethyl]-1H-imidazole; 1-(4-Chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one

Safety Flags
Safety Notes

Azole antifungal effective against Malassezia; good safety profile in cosmetic concentrations; not approved as OTC antidandruff active in the US.

Function & Common Use

Function

Preservative, Antidandruff, Antifungal

Category

Preservatives

Common In

Anti-dandruff shampoos, scalp treatments, antifungal creams

Origin

Synthetic

Concentration Limits

India (CDSCO)

0.5%

EU Cosmetics Reg.

0.5%

US FDA (21 CFR)

None (not in FDA monograph)

Korea (MFDS)

0.5%

Format restriction: None

Baby restriction: No

Pregnancy: No

IFRA: No

Frequently Asked Questions

Is Climbazole safe to use in skincare?

Climbazole has a Low concern rating from The Clean Sheet. Azole antifungal effective against Malassezia; good safety profile in cosmetic concentrations; not approved as OTC antidandruff active in the US.

Is Climbazole allowed in India?

Climbazole is currently classified as "Permitted" under Indian cosmetics regulations. The maximum permitted concentration is 0.5%.

What is Climbazole used for in cosmetics?

Climbazole functions as: Preservative, Antidandruff, Antifungal. It is commonly found in: Anti-dandruff shampoos, scalp treatments, antifungal creams.

Can Climbazole cause an allergic reaction?

Yes. Climbazole has an allergen flag (No). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.

Is Climbazole safe for babies?

Climbazole has baby/child restrictions: No. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Not listed
Korea (MFDS)
Permitted
Australia (TGA)
Permitted
Canada (NHPID)
Permitted

EU Annex: Annex V (permitted preservative)

Identifiers

CAS38083-17-9
EC253-775-4

Want to check if your product contains Climbazole?

Analyse a Product
WhatsApp Community

Join The Clean Sheet™ community

Science-backed beauty tips, ingredient alerts, and early access. Straight to your WhatsApp.

Join for free →