Chlorobutanol
1,1,1-Trichloro-2-methyl-2-propanol
Central nervous system depressant at high doses; potential endocrine disrupting properties; not recommended in products for infants or during pregnancy; EU restricts use in aerosols.
Function & Common Use
Preservative, Antimicrobial
Preservatives
Eye drops (pharmaceutical), ear preparations, injectable pharmaceutical products; limited cosmetic use
Synthetic
Concentration Limits
0.5%
0.5%
0.5%
0.5%
Format restriction: Not to be used in aerosol products; EU: not to be used in oral hygiene products
Baby restriction: Yes
Pregnancy: Yes
IFRA: No
Frequently Asked Questions
Is Chlorobutanol safe to use in skincare?
Chlorobutanol has a High concern rating. Central nervous system depressant at high doses; potential endocrine disrupting properties; not recommended in products for infants or during pregnancy; EU restricts use in aerosols.
Is Chlorobutanol allowed in India?
Chlorobutanol is currently classified as "Restricted" under Indian cosmetics regulations. The maximum permitted concentration is 0.5%.
What is Chlorobutanol used for in cosmetics?
Chlorobutanol functions as: Preservative, Antimicrobial. It is commonly found in: Eye drops (pharmaceutical), ear preparations, injectable pharmaceutical products; limited cosmetic use.
Can Chlorobutanol cause an allergic reaction?
Yes. Chlorobutanol has an allergen flag (No). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.
Is Chlorobutanol safe for babies?
Chlorobutanol has baby/child restrictions: Yes. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.
Regulatory Status
EU Annex: Annex V (permitted preservative)
Identifiers
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