Phytosphingosine
Phytosphingosine / 2-amino-1,3,4-octadecanetriol
Ceramide precursor; antimicrobial against C. acnes; anti-inflammatory; skin-identical; produced by yeast fermentation; used in acne and sensitive skin formulations; enhances skin barrier lipid synthesis
Function & Common Use
Skin Conditioning / Antimicrobial
Active Ingredient
Acne products barrier creams anti-irritant serums
Yeast (biotechnological)
Concentration Limits
No limit
No limit
No specific 21 CFR cosmetic limit identified in source checked; EU limit reference: None
No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category
Format restriction: Leave-on
Pregnancy: No specific restriction identified in source checked; standard cosmetic use
Frequently Asked Questions
Is Phytosphingosine safe to use in skincare?
Phytosphingosine has a Low concern rating from The Clean Sheet. Ceramide precursor; antimicrobial against C. acnes; anti-inflammatory; skin-identical; produced by yeast fermentation; used in acne and sensitive skin formulations; enhances skin barrier lipid synthesis
Is Phytosphingosine allowed in India?
Phytosphingosine is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.
What is Phytosphingosine used for in cosmetics?
Phytosphingosine functions as: Skin Conditioning / Antimicrobial. It is commonly found in: Acne products barrier creams anti-irritant serums.
Regulatory Status
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies
Identifiers
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Reviewed by The Clean Sheet, with our verdict.