2% Ceramide-Peptide Barrier Repair Moisturizer
Excellent2% Ceramide-Peptide Barrier Repair Moisturizer
Dry skin, compromised barrier, eczema-prone, sensitive skin

An evidence-based barrier repair moisturiser built around a five-ceramide complex (Ceramide 1, 2, 3, 4, 6 II) with Cetyl-PG Hydroxyethyl Palmitamide (a synthetic ceramide analog), …

An evidence-based barrier repair moisturiser built around a five-ceramide complex (Ceramide 1, 2, 3, 4, 6 II) with Cetyl-PG Hydroxyethyl Palmitamide (a synthetic ceramide analog), five skin-activating peptides, and Laminaria Digitata polysaccharide. This mirrors the three-ceramide plus cholesterol approach used in barrier repair studies (Elias et al.), extended with peptide support. Calophyllum Inophyllum (Tamanu) Oil provides anti-inflammatory and wound-healing calophyllolide content. Chia Seed Oil (Salvia Hispanica) is linoleic acid-dominant (non-comedogenic, anti-inflammatory). Shea Butter adds thick occlusive emolliency. Caprylic/Capric Triglyceride (MCT) as position 2 oil phase provides lightweight primary emolliency. No fragrance, no parabens, no synthetic dyes.
All ingredients comply with EU Regulation 1223/2009 and India CDSCO cosmetics regulations. No fragrance allergens above EU threshold, no parabens, no azo dyes. Calophyllum Inophyllum (Tamanu) Seed Oil: phototoxic potential has been noted in isolated calophyllolide studies, but cosmetic formulation concentrations are well below the threshold of concern as assessed by the SCCS. Steareth-21 is an ethoxylated emulsifier. Ethoxylation is a manufacturing process that can produce 1,4-dioxane as a by-product — a substance of regulatory concern. The manufacturer is required under EU GMP rules to test and confirm that 1,4-dioxane impurity levels are within acceptable limits. This is standard quality control practice across the industry, not unique to this ingredient, but it is worth knowing. Phenoxyethanol appears near the end of the list, confirming the preservative is well within the EU/India 1% permitted maximum.
The five ceramides — Ceramide 1 (EOS), 2 (NS), 3 (NP), 4 (EOH), and 6 II (AP) — cover all the key ceramide classes present in healthy skin. Each plays a different role in building the layered lipid structure of the stratum corneum. Ceramide 1 anchors the lamellar bodies; Ceramide 2 is the most abundant in healthy skin; Ceramide 3 regulates barrier permeability; Ceramide 6 II is specifically associated with barrier recovery after damage. The ceramide analog Cetyl-PG Hydroxyethyl Palmitamide integrates into this structure alongside Laminaria Digitata seaweed polysaccharide, which helps create the right environment for ceramide delivery. Chia Seed Oil is linoleic acid-dominant — this is important because linoleic acid deficiency is mechanistically linked to impaired barrier formation, and many common oils (including traditional Indian coconut and sesame) are oleic acid-dominant and do not correct this. Tamanu Oil's calophyllolide content brings anti-inflammatory and wound-healing properties. Saccharide Isomerate has clinical evidence for maintaining 72-hour water binding in the skin.
The ingredient list uses correct INCI nomenclature throughout and is verified on the brand website. The ceramide and peptide inclusions are genuine and positioned in the list in a way consistent with functional concentrations. The brand states a '2% Ceramide-Peptide' total but does not disclose how that 2% is distributed across the five ceramides and five peptides individually. Tamanu Oil's therapeutic benefits are referenced in brand communications but no product-specific clinical studies have been published. No clinical test data has been published for this formula.
Cruelty-free brand. No synthetic fragrance, no parabens. Steareth-21 is petrochemical-derived and produced through ethoxylation. Independent RSPO certification for Shea Butter and Caprylic/Capric Triglyceride (coconut/palm-derived) has not been confirmed. Sustainability details for Chia Seed Oil and Tamanu Oil sourcing are not disclosed.
Barrier compromise is chronically underdiagnosed in India, where harsh soaps, hard water, and air conditioning create a cycle of transepidermal water loss (TEWL) and sensitisation. The five-ceramide complex here mirrors the lipid composition of healthy skin and is supported by clinical literature for eczematous and xerotic skin conditions. Linoleic acid from Chia Seed Oil is particularly relevant: linoleic acid deficiency (caused by oleic acid-dominant oils in traditional Indian skincare) is now understood to be mechanistically linked to compromised barrier formation. Tamanu Oil's anti-inflammatory calophyllolide content also resonates for Indian skin types prone to secondary inflammation from barrier insults. Suitable for post-treatment barrier recovery after active serums (retinoids, AHAs, BHAs).
| Ingredient | Note | Status |
|---|---|---|
Aqua (Water) | Solvent base | Safe |
Caprylic/Capric Triglyceride | MCT from coconut/palm; primary emollient phase. Lightweight, non-comedogenic, excellent skin feel | Safe |
Centella Asiatica (Cica) Extract | Position 3 confirms high concentration; madecassoside and asiaticoside for wound-healing and barrier support | Safe |
Aloe Barbadensis (Aloe Vera) Extract | Soothing aqueous phase component | Safe |
Glyceryl Stearate SE | Self-emulsifying emulsifier; creates stable oil-water emulsion | Safe |
Dicaprylyl Carbonate | Lightweight emollient ester; provides dry, non-greasy skin feel | Safe |
Steareth-21 | Ethoxylated emulsifier. Manufacturer must confirm 1,4-dioxane impurity below EU/India acceptable limits per GMP | Note |
Glycerin | Humectant, barrier-supportive | Safe |
Ceramide 1 | Ceramide EOS; critical for lamellar body assembly in stratum corneum. Anchors lipid bilayer structure | Safe |
Ceramide 2 | Ceramide NS; dominant ceramide class in healthy SC lipid profile | Safe |
Ceramide 3 | Ceramide NP; regulates SC permeability barrier | Safe |
Ceramide 4 | Ceramide EOH; lamellar body structural component | Safe |
Ceramide 6 II | Ceramide AP; associated with barrier recovery after mechanical, UV, or chemical insult | Safe |
Laminaria Digitata (Oarweed) Extract | Marine polysaccharide humectant and emollient; supports ceramide delivery environment | Safe |
Cetyl-PG Hydroxyethyl Palmitamide | Synthetic pseudo-ceramide (ceramide 3 analog); integrates into SC lamellar structure for barrier repair | Safe |
Tripeptide-1 | Signal peptide; stimulates collagen I, III, and fibronectin | Safe |
Hexapeptide-9 | Stimulates hemidesmosome proteins; skin firming and ECM support | Safe |
Palmitoyl Tripeptide-5 | TGF-beta mimetic; reduces collagen breakdown via TIMP-1 | Safe |
Palmitoyl Pentapeptide-4 | Matrixyl; stimulates collagen I, III, and hyaluronan synthesis | Safe |
Palmitoyl Tetrapeptide-7 | Inhibits excess IL-6; anti-glycation and anti-inflammatory | Safe |
Butyrospermum Parkii (Shea) Butter | Rich occlusive emollient; oleic-dominant but with significant stearic acid. Seals moisture for dry/compromised skin | Safe |
Calophyllum Inophyllum Seed (Tamanu) Oil | Anti-inflammatory and wound-healing from calophyllolide content. Traditional therapeutic use for barrier compromise and scarring | Safe |
Salvia Hispanica Seed (Chia) Oil | Linoleic acid-dominant fatty acid profile (non-comedogenic). Corrects linoleic acid deficiency mechanistically linked to barrier dysfunction | Safe |
Glyceryl Glucoside | Humectant and barrier-supportive; supports aquaporin-3 water channel function | Safe |
Saccharide Isomerate | C-Xyloside NMF precursor; 72-hour water binding and cornified envelope reinforcement | Safe |
Sodium Acrylates Copolymer | Polymer thickener/stabiliser | Safe |
Sodium Polyacrylate | Polymer thickener, water-absorbent | Safe |
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate | Tinogard TT; high-performance antioxidant preventing oxidative degradation of oil phase ingredients | Safe |
Polysorbate 20 | Non-ionic surfactant/solubiliser | Safe |
Citric Acid | pH adjustment | Safe |
Sodium Citrate | Buffer salt | Safe |
Sodium Gluconate | Chelating agent, supports preservative system | Safe |
Phenoxyethanol | Preservative; late-list position confirms within EU/India 1% limit | Note |
Ethylhexylglycerin | Preservative booster, low concern | Safe |
Ingredients listed in INCI order as declared on product packaging. Position reflects approximate concentration (high → low).
Clean Sheet Scores are generated by analysing every ingredient against India, EU, US & Korean safety regulations. No brand sponsorship. No affiliate relationships. Independent science-backed analysis only.
The Clean Sheet does not use fear-based ingredient labels. We assess products through a structured evidence hierarchy:
- What global regulations say
- What toxicology says
- What the formula concentration shows
- What the product format changes
- What the intended user needs
- What testing evidence proves
- What the brand is claiming