Ingredient Directory
Low ConcernVegan

Ceramide NP

N-(2-Hydroxypalmitoyl)phytosphingosine / Ceramide 3

Safety Notes

Most abundant ceramide in the stratum corneum; critical for barrier function; synthetic version identical to skin-native ceramide; depleted in eczema/atopic conditions; typically used in combination with other ceramides and cholesterol for synergistic effect; no safety concerns

Function & Common Use

Function

Skin Conditioning / Barrier Repair

Category

Emollient

Common In

Moisturisers barrier creams sensitive skin serums

Origin

Synthetic (biotechnological)

Concentration Limits

India (CDSCO)

No limit

EU Cosmetics Reg.

No limit

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked

Korea (MFDS)

No specific MFDS limit identified in source checked; verify if ingredient is used in a Korean functional cosmetic category

Format restriction: Leave-on

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Ceramide NP safe to use in skincare?

Ceramide NP has a Low concern rating from The Clean Sheet. Most abundant ceramide in the stratum corneum; critical for barrier function; synthetic version identical to skin-native ceramide; depleted in eczema/atopic conditions; typically used in combination with other ceramides and cholesterol for synergistic effect; no safety concerns

Is Ceramide NP allowed in India?

Ceramide NP is currently classified as "Permitted" under Indian cosmetics regulations. No concentration limit is specified for India.

What is Ceramide NP used for in cosmetics?

Ceramide NP functions as: Skin Conditioning / Barrier Repair. It is commonly found in: Moisturisers barrier creams sensitive skin serums.

TCS Assessment
Low Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Canada (NHPID)
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

Identifiers

CAS100403-19-8
ECN/A

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