Ingredient Directory
Medium ConcernVegan Evaluator Flag

Sodium Hydroxymethylglycinate

Sodium N-(hydroxymethyl)glycinate

Safety Flags
Allergen: Yes
Safety Notes

Formaldehyde-releasing preservative; releases formaldehyde slowly in aqueous solutions; risk of sensitization particularly in individuals already sensitized to formaldehyde; EU requires disclosure labeling when free formaldehyde exceeds 0.05%; avoid in products for children and formaldehyde-sensitive individuals.

Function & Common Use

Function

Preservative, Antimicrobial

Category

Preservatives

Common In

Shampoos, conditioners, body washes, facial cleansers, baby wipes (with caution)

Origin

Synthetic

Concentration Limits

India (CDSCO)

0.5%

EU Cosmetics Reg.

0.5%

US FDA (21 CFR)

0.5%

Korea (MFDS)

0.5%

Format restriction: EU: must not be used in aerosol products; formaldehyde-releasing preservative - label warning required if free formaldehyde exceeds 0.05%

Baby restriction: Yes

Pregnancy: No

IFRA: No

Frequently Asked Questions

Is Sodium Hydroxymethylglycinate safe to use in skincare?

Sodium Hydroxymethylglycinate has a Medium concern rating. Formaldehyde-releasing preservative; releases formaldehyde slowly in aqueous solutions; risk of sensitization particularly in individuals already sensitized to formaldehyde; EU requires disclosure labeling when free formaldehyde exceeds 0.05%; avoid in products for children and formaldehyde-sensitive individuals.

Is Sodium Hydroxymethylglycinate allowed in India?

Sodium Hydroxymethylglycinate is currently classified as "Permitted" under Indian cosmetics regulations. The maximum permitted concentration is 0.5%.

What is Sodium Hydroxymethylglycinate used for in cosmetics?

Sodium Hydroxymethylglycinate functions as: Preservative, Antimicrobial. It is commonly found in: Shampoos, conditioners, body washes, facial cleansers, baby wipes (with caution).

Can Sodium Hydroxymethylglycinate cause an allergic reaction?

Yes. Sodium Hydroxymethylglycinate has an allergen flag (Yes). If you have sensitive skin or known fragrance/contact allergies, patch-test products containing this ingredient before full use.

Is Sodium Hydroxymethylglycinate safe for babies?

Sodium Hydroxymethylglycinate has baby/child restrictions: Yes. Avoid using products containing this ingredient on infants unless specifically formulated and labelled for baby use.

TCS Assessment
Medium Concern
Data Confidence
High
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Permitted
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Permitted
Canada (NHPID)
Permitted

EU Annex: Annex V (permitted preservative)

Identifiers

CAS70161-44-3
EC274-357-8

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