Ingredient Directory
Low ConcernVegan Evaluator Flag

Alpha-Arbutin

4-Hydroxyphenyl alpha-D-glucopyranoside

Safety Notes

Hydroquinone precursor, SCCS review of safety ongoing as of 2024-2026; current EU restriction proposal: max 2% face leave-on; check latest SCCS opinion for current restriction status

Function & Common Use

Function

Active (Brightening / Hyperpigmentation)

Category

Active Ingredient

Common In

Brightening serums moisturisers

Origin

Vegetable / Synthetic

Concentration Limits

India (CDSCO)

No formal limit

EU Cosmetics Reg.

EU Annex III restriction in review, check current status; proposed 2% face 0.5% body leave-on

US FDA (21 CFR)

No specific 21 CFR cosmetic limit identified in source checked; EU limit reference: EU Annex III restriction in review, check current status; proposed 2% face 0.5% body leave-on

Korea (MFDS)

2% (whitening functional cosmetic)

Format restriction: Leave-on

Pregnancy: No specific restriction identified in source checked; standard cosmetic use

Frequently Asked Questions

Is Alpha-Arbutin safe to use in skincare?

Alpha-Arbutin has a Low concern rating from The Clean Sheet. Hydroquinone precursor, SCCS review of safety ongoing as of 2024-2026; current EU restriction proposal: max 2% face leave-on; check latest SCCS opinion for current restriction status

Is Alpha-Arbutin allowed in India?

Alpha-Arbutin is currently classified as "Permitted" under Indian cosmetics regulations. The maximum permitted concentration is No formal limit.

What is Alpha-Arbutin used for in cosmetics?

Alpha-Arbutin functions as: Active (Brightening / Hyperpigmentation). It is commonly found in: Brightening serums moisturisers.

TCS Assessment
Low Concern
Data Confidence
Medium
Based on peer-reviewed safety data, regulatory status, and expert review by The Clean Sheet panel.

Regulatory Status

India (CDSCO)
Permitted
EU
Restricted pending
US FDA
Permitted
Korea (MFDS)
Permitted
Australia (TGA)
Cosmetic ingredient; standard TGA cosmetic framework applies; no therapeutic goods listing required unless therapeutic claims are made
Canada (NHPID)
Not specifically listed as restricted cosmetic ingredient in NHPID source checked; standard Health Canada cosmetic notification applies

EU Annex: EU Annex III

Identifiers

CAS84380-01-8
ECN/A

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